Personalized health planning is the key feature of personalized health care as it anticipates the individual’s specific health needs and develops a coordinated means to achieve them. The personal health plan is developed collaboratively by the provider and the patient and utilizes comprehensive health risk assessment as the basis for both enhancing health and well-being and mitigating and tracking disease over time. Greater collaboration between patient and provider replaces the traditional physician-dominated dialogue with more effective patient-physician partnerships and continuity of care. The patient’s needs and goals for their health, wellness, and disease mitigation drive the planning process and nature of the plan. The personalized health planning framework provides an operational care model for delivering personalized, proactive, patient-driven care to individuals with a diverse range of needs.